カタログ製品コード : C-EK21492
Mouse Endoglin/CD105 ELISA kit
| 24T | ¥55,200 | (¥2,300/T) (税別) |
| 48T | ¥69,200 | (¥1,442/T) (税別) |
| 96T | ¥78,000 | (¥813/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | Endoglin/CD105 | Mouse | 156.25 - 10000 pg/ml | 20 μl | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against TGF-β1 |
| Mouse TGF-β1 Standard, lyophilized |
| TGF-β1 Detect Antibody |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| washing Buffer (20×) |
| HCl |
| NaOH |
| Plate Covers |
■キーワード :
Mus musculus,Mouse,Endoglin,Cell surface MJ7/18 antigen,Eng,Edg,CD105
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse Endoglin. The Mouse Endoglin/CD105 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Endoglin also known as CD105 is a type I membrane glycoprotein located on cell surfaces and is part of the TGF-β receptor complex. It is involved in modulating a response to the binding of TGF-β1, TGF-β3, activin-A, BMP-2 and BMP-7. It has been postulated that Endoglin is involved in the cytoskeletal organization affecting cell morphology and migration. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. Experimental mice without the Endoglin gene die due to cardiovascular abnormalities. In humans, Endoglin may be involved in the autosomal dominant disorder known as hereditary hemorrhagic telangiectasia (HHT) type 1. This condition leads to frequent nose bleeds, telangiectases on skin and mucosa and may cause arteriovenous malformations in different organs including brain, lung, and liver.
