カタログ製品コード : C-EK2042/2
Mouse IL-4 ELISA kit
| 24T | ¥55,200 | (¥2,300/T) (税別) |
| 48T | ¥69,200 | (¥1,442/T) (税別) |
| 96T | ¥78,000 | (¥813/T) (税別) |
標準納期 : 1週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | IL-4 | Mouse | 7.81 - 500 pg/ml | 20 μl | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against Mouse IL-4 |
| Mouse IL-4 Standard, lyophilized |
| Mouse IL-4 Detect Antibody |
| Standard Diluent |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| washing Buffer (20×) |
| Plate Covers |
■キーワード :
Mus musculus,Mouse,Interleukin-4,IL-4,B-cell IgG differentiation factor,B-cell growth factor 1,B-cell stimulatory factor 1,BSF-1,IGG1 induction factor,Lymphocyte stimulatory factor 1,Il4,Il-4
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-4. The Mouse IL-4 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 4 (IL-4) is an approximately 18-20 kDa monomeric cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Mouse IL-4 is synthesized as a 140 amino acid (aa) precursor with a 20 aa signal sequence and a 120 aa mature chain and mature mouse IL-4 shares 43%, and 63% aa sequence identity with human and rat IL-4.
IL-4 is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell. It is closely related and has functions similar to IL-13.
IL-4 also has been shown to drive mitogenesis, dedifferentiation, and metastasis in rhabdomyosarcoma. IL-4, along with other Th2 cytokines, is involved in the airway inflammation observed in the lungs of patients with allergic asthma.
