カタログ製品コード : C-EK12282
Human TrkB/NTRK2 ELISA kit
| 24T | ¥58,200 | (¥2,425/T) (税別) |
| 48T | ¥72,200 | (¥1,504/T) (税別) |
| 96T | ¥81,000 | (¥844/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | TrkB/NTRK2 | Human | 15.63 - 1000 pg/ml | 100 μl (prediluted) | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against TrkB |
| Human TrkB Standard, lyophilized |
| TrkB Detect Antibody |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,neurotrophic receptor tyrosine kinase 2,OBHD,TRKB,trk-B,EIEE58,GP145-TrkB
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human TrkB. The Human TrkB/NTRK2 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, a receptor for brain-derived neurotrophic factor (BDNF), is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor exclusively expressed in neurons of the central nervous system. TrkB mediates the multiple effects of neurotrophic factors such as BDNF, neurotrophin-4 (NT-4), and neurotrophin-3 (NT-3), which includes neuronal differentiation and survival. It has two distinct binding regions for BDNF within the extracellular domain with high affinity. Upon neurotrophin binding, TrkB phosphorylates itself and the downstream molecular members of the related signal pathways.
TrkB has been shown to play an important role in tumorigenesis and metastasis, and mutations in this gene are associated with obesity and mood disorders. Accordingly, BDNF/TrkB signaling is thought to be a potential therapeutic target for schizophrenia.
