カタログ製品コード : C-EK12062
Human CD117/c-Kit ELISA kit
| 24T | ¥47,000 | (¥1,958/T) (税別) |
| 48T | ¥61,000 | (¥1,271/T) (税別) |
| 96T | ¥69,800 | (¥727/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | CD117/c-Kit | Human | 31.25 - 2000 pg/ml | 20 μl (prediluted) | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against CD117 |
| Human CD117 Standard, lyophilized |
| CD117 Detect Antibody |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Mast/stem cell growth factor receptor Kit,SCFR,Piebald trait protein,PBT,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,p145 c-kit,v-kit Hardy-Zuckerman 4 feline sarcoma viral,CD117,MASTC,PBT,SCFR
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CD117. The Human CD117/c-Kit ELISA is for research use only. Not for diagnostic or therapeutic procedures.
CD117, also known as c-Kit, is a cytokine receptor expressed on the surface of hematopoietic stem cells (HSC) as well as other cell types. CD117 is a receptor tyrosine kinase type III, which binds to stem cell factor. When this receptor binds to stem cell factor, it forms a dimer that activates its intrinsic tyrosine kinase activity, which in turn phosphorylates and activates signal transduction molecules that propagate the signal in the cell. Signaling through CD117 plays a role in cell survival, proliferation, and differentiation.
HSC, multipotent progenitors (MPP), and common myeloid progenitors (CMP) express high levels of CD117. Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.
