カタログ製品コード : C-EK12022
Human Angiotensinogen/AGT/SerpinA8 ELISA kit
| 24T | ¥70,200 | (¥2,925/T) (税別) |
| 48T | ¥84,200 | (¥1,754/T) (税別) |
| 96T | ¥93,000 | (¥969/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | Angiotensinogen/AGT/SerpinA8 | Human | 312.50 - 20000 pg/ml | 100 μl (prediluted) | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against AGT |
| Human AGT Standard, lyophilized |
| AGT Detect Antibody |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Angiotensinogen,Serpin A8,AGT,SERPINA8
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human AGT. The Human Angiotensinogen/AGT/SerpinA8 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Angiotensinogen (AGT), also known as SerpinA8, is a member of the serpin family. It is an α-2-globulin produced constitutively and released into the circulation mainly by the liver. AGT is an essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. AGT is cleaved into three chains: Angiotensin-1, Angiotensin-2, and Angiotensin-3.
Defects in AGT are associated with susceptibility to essential hypertension and renal tubular dysgenesis (RTD). Several serpins (antithrombin, maspin, pigment epithelial-derived factor, and kallistatin) have been recently shown to exert an antiangiogenic activity, suggesting a common mechanism of endothelial cell proliferation and migration. Angiotensinogen/AGT and its renin-cleaved product, are also angiogenesis inhibitors, both in vitro and in vivo at concentrations within the range of those observed in plasma.
