カタログ製品コード : C-EK11872
Human ErbB3/HER3 ELISA kit
| 24T | ¥55,200 | (¥2,300/T) (税別) |
| 48T | ¥69,200 | (¥1,442/T) (税別) |
| 96T | ¥78,000 | (¥813/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | ErbB3/HER3 | Human | 93.75 - 6000 pg/ml | 10 μl | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against ErbB3 |
| Human ErbB3 Standard, lyophilized |
| ErbB3 Detect Antibody |
| Standard Diluent |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Receptor tyrosine-protein kinase erbB-3,Proto-oncogene-like protein c-ErbB-3,Tyrosine kinase-type cell surface receptor HER3,ERBB3,HER3,2.7.10.1
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human ErbB3. The Human ErbB3/HER3 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Receptor tyrosine-protein kinase ErbB3, also known as HER3 (human epidermal growth factor receptor 3), is a membrane bound protein that in humans is encoded by the ERBB3 gene. ErbB3 is a member of the epidermal growth factor receptor (EGFR/ERBB) family. ErbB3, like the other members of the EGFR family, consists of an extracellular ligand binding domain, a transmembrane domain, and an intracellular domain. ErbB3 has been shown to bind the ligands heregulin and NRG-2, but it can’t mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicate in numerous cancers, including prostate, bladder, and breast tumors.
