カタログ製品コード : C-EK11802
Human PRLR ELISA kit
| 24T | ¥100,200 | (¥4,175/T) (税別) |
| 48T | ¥114,200 | (¥2,379/T) (税別) |
| 96T | ¥123,000 | (¥1,281/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | PRLR | Human | 15.63 - 1000 pg/ml | 50 μl | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against PRLR |
| Human PRLR Standard, lyophilized |
| PRLR Detect Antibody |
| Standard Diluent |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,prolactin receptor,HPRL,MFAB,hPRLrI,RI-PRLR
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human PRLR. The Human PRLR ELISA is for research use only. Not for diagnostic or therapeutic procedures.
The prolactin receptor (PRLR), a cytokine receptor— encoded by a gene on chromosome 5p13-14— interacts with prolactin as a transmembrane receptor. Thus it contains an extracellular region that binds prolactin, a transmembrane region, and a cytoplasmatic region. PRLR is widely expressed in breast, placenta, kidney, liver and pancreas and also activated by growth hormone (GH) and human placental lactogen (hPL) in addition to prolactin. It has been well documented that abnormity of PRLR is closely related to the pathogenesis, progression and prognosis of cancers including breast cancer. Specific binding to PRLR can stimulate the breast cancer cells to grow and certain antagonists which bind but do not dimerize PRLR can inhibit the growth of breast cancer cells. Several isoforms have been described, and the soluble form are unable to transduce prolactin signaling.
