カタログ製品コード : C-EK11682
Human IGFBP-3 ELISA kit
| 24T | ¥55,200 | (¥2,300/T) (税別) |
| 48T | ¥69,200 | (¥1,442/T) (税別) |
| 96T | ¥78,000 | (¥813/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | IGFBP-3 | Human | 125 - 8000 pg/ml | 20 μl | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against IGFBP-3 |
| Human IGFBP-3 Standard, lyophilized |
| IGFBP-3 Detect Antibody |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Insulin-like growth factor-binding protein 3,IBP-3,IGF-binding protein 3,IGFBP-3,IGFBP3,IBP3
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IGFBP-3. The Human IGFBP-3 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Insulin-like growth factor binding protein 3 (IGFBP-3), is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins (IGFBP-1 to IGFBP-6) that have highly conserved structures and bind IGF-1 and IGF-2 with high affinity. IGFBP-3 is the main IGF transport protein in the bloodstream. It interacts with cell-surface proteins, affecting cell signaling from outside the cell or after internalization, and also enters the cell nucleus where it binds to nuclear hormone receptors and other ligands.
Based on cell growth experiments, animal cancer models, and epidemiological studies, it appears that IGFBP-3 functions as a low-penetrance tumor suppressor gene. Dysregulation of IGFBP-3 has been implicated in many cancers. Serum levels of IGFBP-3 can be used to screen for growth hormone deficiency. Serum levels of IGFBP-3 are decreased in AIDS, uncontrolled diabetes mellitus, trauma, and severe burns.
