カタログ製品コード : C-EK11642
Human Chitinase 3-like 1/CHI3L1 ELISA kit
| 24T | ¥55,200 | (¥2,300/T) (税別) |
| 48T | ¥69,200 | (¥1,442/T) (税別) |
| 96T | ¥78,000 | (¥813/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | Chitinase 3-like 1/CHI3L1 | Human | 15.63 - 1000 pg/ml | 50 μl | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against CHI3L1 |
| Human CHI3L1 Standard, lyophilized |
| CHI3L1 Detect Antibody |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Chitinase-3-like protein 1,39 kDa synovial protein,Cartilage glycoprotein 39,CGP-39,GP-39,hCGP-39,YKL-40,CHI3L1
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CHI3L1. The Human Chitinase-3-like 1/CHI3L1 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Chitinase-3-like 1 (CHI3L1) is secreted by various cell-types including macrophages, chondrocytes, and some types of cancer cells. The exact physiological role of CHI3L1 is not known, but it has been implicated in development, inflammatory disease (such as asthma, and cancer progression).
CHI3L1 is a Th2 promoting cytokine that is present at high levels in the tumor micro-environment and in the serum of cancer patients. Elevated levels of CHI3L1 correlate strongly with stage and outcome of various types of cancer, which establish CHI3L1 as a biomarker of disease severity. Targeting CHI3L1 with neutralizing antibodies has been proven effective as a treatment in animal models of glioblastoma multiforme. CHI3L1 is able to promote angiogenesis through VEGFdependent and independent pathways. CHI3L1 also enhances tumor survival in response to γ-irradiation.
