カタログ製品コード : C-EK11612
Human TRAIL/TNFSF10 ELISA kit
| 24T | ¥47,000 | (¥1,958/T) (税別) |
| 48T | ¥61,000 | (¥1,271/T) (税別) |
| 96T | ¥69,800 | (¥727/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | TRAIL/TNFSF10 | Human | 62.50 - 4000 pg/ml | 20 μl | 血清、血漿、細胞培養上清 |
|
■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against TRAIL |
| Human TRAIL Standard, lyophilized |
| TRAIL Detect Antibody |
| Standard Diluent |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Tumor necrosis factor ligand superfamily member 10,Apo-2 ligand,Apo-2L,TNF-related apoptosis-inducing ligand,Protein TRAIL,TNFSF10,APO2L,TRAIL,CD253
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human TRAIL. The Human TRAIL/TNFSF10 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
TNF-related apoptosis-inducing ligand (TRAIL) also known as CD253 or TNFSF10, is a cytokine that is produced and secreted by most normal tissue cells. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII). The process of apoptosis is caspase-8-dependent. Caspase-8 activates downstream effector caspases including procaspase-3, -6, and -7, leading to activation of specific kinases. TRAIL also binds the receptors DcR1 and DcR2, which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). DcR1 functions as a TRAIL-neutralizing decoy-receptor. The cytoplasmic domain of DcR2 is functional and activates NF-κB. In cells expressing DcR2, TRAIL binding therefore activates NF-κB, leading to transcription of genes known to antagonize the death signaling pathway and/or to promote inflammation.
