カタログ製品コード : C-EK11442

Human M-CSF ELISA kit

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24T ¥73,200 (¥3,050/T) (税別)
48T ¥87,200 (¥1,817/T) (税別)
96T ¥96,000 (¥1,000/T) (税別)
標準納期 : 2週間
メーカー名 遺伝子名 種交差性 測定範囲 サンプル量 適用サンプル ドキュメント
MultiSciences M-CSF Human 31.25 - 2000 pg/ml 20 μl 血清、血漿、細胞培養上清

保存方法 :

キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。

構成内容 :

96-well polystyrene microplate coated with a monoclonal antibody against M-CSF
Human M-CSF Standard, lyophilized
M-CSF Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

キーワード :

Homo sapiens,Human,Macrophage colony-stimulating factor 1,CSF-1,M-CSF,MCSF,Lanimostim,CSF1

ターゲット情報 :

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human M-CSF. The Human M-CSF ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Macrophage colony-stimulating factor (M-CSF), also known as colony stimulating factor 1 (CSF1), is a secreted cytokine released by osteoblasts. It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis. M-CSF has been described to play a role in renal pathology including Acute kidney injury (AKI) and Chronic Renal Failure (CRF). The chronic activation of monocytes can lead to multiple metabolic, hematologic and immunologic abnormalities in patients with CRF. In the context of AKI, M-CSF has been implicated in promoting repair following AKI, but also been described in an opposing role, driving proliferation of a pro-inflammatory macrophage phenotype.