カタログ製品コード : C-EK11232
Human sTNF RII/TNFRSF1B ELISA kit
| 24T | ¥55,200 | (¥2,300/T) (税別) |
| 48T | ¥69,200 | (¥1,442/T) (税別) |
| 96T | ¥78,000 | (¥813/T) (税別) |
標準納期 : 2週間 |
製品詳細
| メーカー名 | 遺伝子名 | 種交差性 | 測定範囲 | サンプル量 | 適用サンプル | ドキュメント |
|---|---|---|---|---|---|---|
| MultiSciences | sTNF RII/TNFRSF1B | Human | 7.81 - 500 pg/ml | 100 μl (prediluted) | 血清、血漿、細胞培養上清 |
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■保存方法 :
キットは未開封の場合、4℃で保管すること。 開封後は標準溶液を-20℃で保存し、他の試薬は4℃で保存すること。
■構成内容 :
| 96-well polystyrene microplate coated with a monoclonal antibody against sTNF RII |
| Human sTNF RII Standard, lyophilized |
| sTNF RII Detect Antibody |
| Standard Diluent |
| Streptavidin-HRP |
| Assay Buffer (10×) |
| Substrate (TMB) |
| Stop Solution |
| Washing Buffer (20×) |
| Plate Covers |
■キーワード :
Homo sapiens,Human,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor receptor 2,TNF-R2,Tumor necrosis factor receptor type II,TNF-RII,TNFR-II,p75,p80 TNF-alpha receptor
■ターゲット情報 :
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human sTNF RII. The Human sTNF RII/TNFRSF1B is for research use only. Not for diagnostic or therapeutic procedures.
Tumor necrosis factor receptor II (TNFRII), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), is a membrane receptor that binds tumor necrosis factor-alpha (TNF-α). This protein and TNF-receptor I form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF - receptor signalling is unknown, however, c-IAP1 is thoughtto potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF- receptor - associated factor 2 (TRAF2), which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
